The Myc/Max/Mad Transcription Factor Network PDF ePub eBook

Books Info:

The Myc/Max/Mad Transcription Factor Network free pdf Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the "big picture" and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.

About Robert N. Eisenman

However, currently we simply cannot present you with details about your Writer Robert N. Eisenman. However, this doesn't mean that any of us fail for my child collection. In addition we request which you assist us in this particular make any difference. For those who have down time and need will hugely take pleasure in should you offer us your data. Any time receiving such responses and data through end users with regards to the The Myc/Max/Mad Transcription Factor Network Publisher Robert N. Eisenman, we all 1st your ex verify. After most of us be sure that most real, simply publish the idea. All of us see why help and also thanks in advance.

Details Book

Author : Robert N. Eisenman
Publisher : Springer-Verlag Berlin and Heidelberg GmbH
Data Published : 23 September 2014
ISBN : 3642421415
EAN : 9783642421419
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 282 pages
Age + : 15 years
Language : English
Rating :

Reviews The Myc/Max/Mad Transcription Factor Network



17 Comments Add a comment




Related eBooks Download


  • Gene Regulation free pdfGene Regulation

    GENE REGULATION deals with the molecular mechanisms of regulation of gene expression in viruses. bacteria and eukaryotes. Role of epigenetic modifications in gene regulation is dealt with in detail..


  • Post-Transcriptional Gene Regulation free pdfPost-Transcriptional Gene Regulation

    Reflecting the rapid progress in the field. the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells..


  • Antisense Technology free pdfAntisense Technology

    Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation..


  • Foreign Gene Expression in Fission Yeast free pdfForeign Gene Expression in Fission Yeast

    Recombinant proteins. produced in cells or microorganisms. play an important role in basic research. medical science and the biotechnology industry. Many foreign gene expression systems using mammalian cells..


  • New Developments in Serotonin Research free pdfNew Developments in Serotonin Research

    The primary objective of this book is to provide readers with up-to-date knowledge of recent advances in serotonin research across different fields. The research topics include the following aspects: The first chapter provides novel evidence supporting the involvement of genetic variants in the serotonin transporter and receptor genes in the aetiology of nicotine dependence and alcoholism through gene-by-gene interaction..


  • The Myc/Max/Mad Transcription Factor Network free pdfThe Myc/Max/Mad Transcription Factor Network

    Download Palace Ebook. Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the "big pict