The Genetics of the Mouse PDF ePub eBook

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The Genetics of the Mouse free pdf This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits. The authors also discuss the importance of accurate phenotyping, which is now performed in the mouse clinics established worldwide and identify the limits of the mouse model, which under certain circumstances can fail to present the phenotype expected from the cognate condition in the human model. For each chapter an up-to-date list of pertinent references is provided. In short, this book offers an essential resource for all scientists who use or plan to use mice in their research.

About Jean Louis Guenet

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Details Book

Author : Jean Louis Guenet
Publisher : Springer-Verlag Berlin and Heidelberg GmbH
Data Published : 09 December 2014
ISBN : 3662442868
EAN : 9783662442869
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 408 pages
Age + : 15 years
Language : English
Rating :

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