Cardiovascular Physiology in the Genetically Engineered Mouse PDF ePub eBook

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Cardiovascular Physiology in the Genetically Engineered Mouse free pdf The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data. The primary objective of a second edition of Cardiovascular Physiology in the Genetically Engineered Mouse is to interpret critically the literature and to provide a framework for the enormous amount of information in this burgeoning field. As in the first edition, the monograph serves as a practical guide for the investigator interested in the functional methods used to characterize the murine cardiovascular phenotype. The monograph is organized into three parts. The first deals with principles of transgenesis and homologous recombination. The second part, which again is the largest, discusses the various techniques used to assess the cardiovascular mechanical, metabolic, and electrophysiologic phenotype. This section is organized in a hierarchical manner- i.e. from isolated myocyte to isolated heart to the intact, anesthetized and conscious mouse. The third part examines techniques used to evaluate murine smooth muscle function, genetic mouse models of hypertrophy and heart failure, and the methods to assess the cardiovascular phenotype in the developing mouse embryo. In addition, newer methods that 'push the envelope', such as magnetic resonance imaging (MRI), positron emission tomography (PET), ultrasound biomicroscopy (UBM), and computed tomography (microCT) are discussed. Expanded and updated, each chapter is richly enhanced with original tables and figures, and in many cases, extensively rewritten when compared with the first edition. An essential and enduring goal of this second edition is to continue to facilitate interactions between the basic science disciplines and help bridge the gap between molecular biology and physiology.

About Brian D Hoit

However, at this time we cannot supply you with info on your Writer Brian D Hoit. Nevertheless doesn't mean we fail to work on her assortment. In addition we ask which you help us in this issue. If you have free time and need will probably greatly enjoy should you tell us all your details. When acquiring these kinds of feedback and info through consumers with regards to the Cardiovascular Physiology in the Genetically Engineered Mouse Founder Brian D Hoit, all of us first her look at. As soon as most of us be certain that many real, just write-up the idea. We understand why support along with thank you beforehand.

Details Book

Author : Brian D Hoit
Publisher : Springer
Data Published : 16 December 2012
ISBN : 146135661X
EAN : 9781461356615
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 420 pages
Age + : 15 years
Language : English
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