Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres Dans la Chimie des Substances Organiques Naturelles (Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic N PDF ePub eBook

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Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres Dans la Chimie des Substances Organiques Naturelles (Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic N free pdf Depuis l'isolement de la creatine par CHEVREUL, en 1832, dans les extraits de viande (44) et son identification par LIEBIG, en r847, l'attention des biochimistes a porte principalement, pendant longtemps, sur le role de l'arginine dans la production de l'uree (I28), sur le cyde de l'ureo- genese (I34) et sur celui de la phosphocreatine (7I) et de la phospho- arginine (r68, I69) dans la contraction musculaire. A la suite de la mise en evidence, d'une part des reactions de trans- amidination expliquant la convertibilite entre l'arginine et un certain nombre de derives guanidiques (28,29,33,73,2 5, 29I, 292), et, d'autre part, du mecanisme complexe de la biosynthese de l'arginine (34, 45, 46, I95, I96) , l'importance du groupement guanidique dans la fixation et le transfert de l'azote organique est devenue beaucoup plus manifeste. Par ailleurs, l'isolement de nouvelles substances dont certaines: la phosphotaurocyamine, la phosphoglycocyamine (280-282), la phospho- 10mb ricine (270), jouent le meme role de phosphagenes que le creatine- et l'argininephosphate (257), amis en evidence la part importante que les derives guanidiques prennent dans la chimie du musde. L'etude de leur biogenese a montre en outre que leur role n'est pas seulement equivalent a l'arginine dans la fixation de l'azote du groupe amidinique, mais qu'ils sont capables de jouer egalement de role de regulateurs du metabolisme azote (258). I. Structure et formation.

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Details Book

Author : P. W. Brian
Publisher : Springer Verlag GmbH
Data Published : 16 December 2011
ISBN : 370917161X
EAN : 9783709171615
Format Book : PDF, Epub, DOCx, TXT
Number of Pages : 600 pages
Age + : 15 years
Language : English
Rating :

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